Exoc3l2 Gene Summary [Mouse]

Predicted to enable SNARE binding activity. Acts upstream of or within in utero embryonic development. Predicted to be part of exocyst. Is expressed in rete testis and tunica albuginea of testis. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Exoc3l2
Official Name
exocyst complex component 3-like 2 [Source:MGI Symbol;Acc:MGI:1921713]
Ensembl ID
ENSMUSG00000011263
Bio databases IDs NCBI: 74463 Ensembl: ENSMUSG00000011263
Aliases exocyst complex component 3-like 2
Synonyms 4933417E01Rik, BMRS, exocyst complex component 3-like 2, Gm19857, XTP7
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Exoc3l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Exocyst complex component Sec6
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • Alzheimer disease
  • Meckel syndrome
  • age-related macular degeneration
  • Meckel-Gruber like syndrome
  • coronary artery disease
  • brain malformation renal syndrome
  • angina pectoris
  • myocardial infarction
  • meckel syndrome type 7
regulated by
  • VEGFA
  • Collagen type I (complex)
  • (R)-3-hydroxybutyric acid
  • WWTR1
  • embryonic stem cells
regulates
role in cell
  • phosphorylation in
  • migration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • filopodia-like projection
  • Nucleus
  • Plasma Membrane
  • perinuclear vesicles
  • actin stress fibers

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Exoc3l2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • exocytosis

Cellular Component

Where in the cell the gene product is active
  • exocyst

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.