Exoc3l2 Gene Summary [Rat]
Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to act upstream of or within in utero embryonic development. Predicted to be part of exocyst. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Exoc3l2 |
| Official Name | exocyst complex component 3-like 2 [Source:RGD Symbol;Acc:1592539] |
| Ensembl ID | ENSRNOG00000017448 |
| Bio databases IDs | |
| Aliases | exocyst complex component 3-like 2 |
| Synonyms | 4933417E01Rik, BMRS, exocyst complex component 3-like 2, Gm19857, XTP7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Exoc3l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Exocyst complex component Sec6
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- Meckel syndrome
- age-related macular degeneration
- Meckel-Gruber like syndrome
- coronary artery disease
- brain malformation renal syndrome
- angina pectoris
- myocardial infarction
- meckel syndrome type 7
regulates
role in cell
- phosphorylation in
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- filopodia-like projection
- Nucleus
- Plasma Membrane
- perinuclear vesicles
- actin stress fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Exoc3l2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- exocytosis
Cellular Component
Where in the cell the gene product is active
- exocyst
Molecular Function
What the gene product does at the molecular level
- protein binding