Cttn

Predicted to enable several functions, including Arp2/3 complex binding activity; profilin binding activity; and proline-rich region binding activity. Involved in intracellular protein transport and regulation of mitophagy. Acts upstream of or within dendritic spine maintenance; negative regulation of extrinsic apoptotic signaling pathway; and substrate-dependent cell migration, cell extension. Located in several cellular components, including cytoskeleton; lamellipodium; and ruffle. Part of voltage-gated potassium channel complex. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system; and sensory organ. Orthologous to human CTTN (cortactin). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cttn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cttn gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cttn gene, providing context for its role in the cell.