Rassf3 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in embryo mesenchyme and tongue. Orthologous to human RASSF3 (Ras association domain family member 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rassf3 |
| Official Name | Ras association (RalGDS/AF-6) domain family member 3 [Source:MGI Symbol;Acc:MGI:2179722] |
| Ensembl ID | ENSMUSG00000025795 |
| Bio databases IDs | |
| Aliases | Ras association (RalGDS/AF-6) domain family member 3 |
| Synonyms | Ras association domain family member 3, Ras association (RalGDS/AF-6) domain family member 3, RASSF5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rassf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SARAH_SF
- Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
- Ubl1_cv_Nsp3_N-like
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- lung adenocarcinoma
- prostatic carcinoma
- prostate cancer
- epithelial cancer
- lung adenocarcinoma formation
- neoplasia
role in cell
- expression in
- growth
- apoptosis
- proliferation
- cell cycle progression
- G1/S phase transition
- ubiquitination in
- repair in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rassf3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- plasma membrane
- microtubule
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding