Pvr Gene Summary [Mouse]
Enables dynein light chain binding activity. Acts upstream of or within cell migration and cell-cell adhesion. Located in cell surface and plasma membrane. Orthologous to human PVR (PVR cell adhesion molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pvr |
| Official Name | poliovirus receptor [Source:MGI Symbol;Acc:MGI:107741] |
| Ensembl ID | ENSMUSG00000040511 |
| Bio databases IDs | |
| Aliases | poliovirus receptor |
| Synonyms | 3830421F03Rik, CD155, D7Ertd458e, HVED, mE4, necl-5, poliovirus receptor, PVS, Taa1, Tage4 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pvr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- Immunoglobulin C1-set domain
- viral receptor
- Immunoglobulin V-Type
- immunoglobulin domain
- cell adhesion molecule binding
- Immunoglobulin like
- dynein light chain binding
- protein binding
- Immunoglobulin V-set domain
Pathways
Biological processes and signaling networks where the Pvr gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- allergic asthma
- contact hypersensitivity
role in cell
- migration
- proliferation
- quantity
- expression in
- degranulation
- motility
- colonization
- frequency
- G0 phase
- G1 phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- cell membrane leading edge