Ebag9 Gene Summary [Mouse]
Acts upstream of or within T cell mediated cytotoxicity and adaptive immune memory response involving T cells and B cells. Located in Golgi apparatus. Is expressed in several structures, including central nervous system; genitourinary system; retina; spleen; and submandibular gland primordium epithelium. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human EBAG9 (estrogen receptor binding site associated antigen 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ebag9 |
| Official Name | estrogen receptor-binding fragment-associated gene 9 [Source:MGI Symbol;Acc:MGI:1859920] |
| Ensembl ID | ENSMUSG00000022339 |
| Bio databases IDs | |
| Aliases | estrogen receptor-binding fragment-associated gene 9 |
| Synonyms | AI835379, EB9, estrogen receptor-binding fragment-associated gene 9, estrogen receptor binding site associated antigen 9, PDAF, RCAS1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ebag9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transmembrane domain
- coiled-coil domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- infection by bacteria
role in cell
- apoptosis
- cytotoxicity
- size
- transmembrane potential
- function
- abnormal morphology
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- perinuclear region
- cellular membrane
- lysosome
- Golgi Apparatus
- ER-to-Golgi intermediate compartment
- Golgi membrane
- late endosomes
- secretory granules
- Golgi vesicles
- cis Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ebag9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell growth
- apoptotic process
- T cell mediated cytotoxicity
Cellular Component
Where in the cell the gene product is active
- secretory granule
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- apoptotic protease activator activity