Calr3 Gene Summary [Mouse]
Enables protein folding chaperone. Predicted to be involved in ERAD pathway and protein folding. Predicted to be located in endoplasmic reticulum lumen and nuclear envelope. Predicted to be active in endoplasmic reticulum membrane. Is expressed in cerebral cortex and telencephalon. Orthologous to human CALR3 (calreticulin 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Calr3 |
| Official Name | calreticulin 3 [Source:MGI Symbol;Acc:MGI:1920566] |
| Ensembl ID | ENSMUSG00000019732 |
| Bio databases IDs | |
| Aliases | calreticulin 3 |
| Synonyms | 1700031L01Rik, 6330586I20Rik, calreticulin 3, CMH19, CRT2, cspn, CT93 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Calr3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calreticulin family
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum lumen
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Calr3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
- cell differentiation
- protein folding
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- endoplasmic reticulum membrane
- endoplasmic reticulum lumen
Molecular Function
What the gene product does at the molecular level
- protein binding involved in protein folding
- calcium ion binding
- unfolded protein binding
- carbohydrate binding