Sumf2 Gene Summary [Mouse]
Enables identical protein binding activity. Predicted to be involved in negative regulation of post-translational protein modification. Is active in endoplasmic reticulum lumen. Orthologous to human SUMF2 (sulfatase modifying factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sumf2 |
| Official Name | sulfatase modifying factor 2 [Source:MGI Symbol;Acc:MGI:1915152] |
| Ensembl ID | ENSMUSG00000025538 |
| Bio databases IDs | |
| Aliases | sulfatase modifying factor 2 |
| Synonyms | 2610040F05RIK, LOC100504797, pFGE, sulfatase modifying factor 2, sulphatase modifying factor 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sumf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme inhibitor activity
- Sulfatase-modifying factor enzyme 1
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sumf2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- metal ion binding