Adat2 Gene Summary [Mouse]
Predicted to enable tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Orthologous to human ADAT2 (adenosine deaminase tRNA specific 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adat2 |
| Official Name | adenosine deaminase, tRNA-specific 2 [Source:MGI Symbol;Acc:MGI:1914007] |
| Ensembl ID | ENSMUSG00000019808 |
| Bio databases IDs | |
| Aliases | adenosine deaminase, tRNA-specific 2 |
| Synonyms | 4933426M09RIK, adenosine deaminase tRNA specific 2, adenosine deaminase, tRNA-specific 2, DEADC1, dJ20N2, dJ20N2.1, TAD2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adat2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytidine_deaminase-like
- MafB19-like deaminase
- Cytidine and deoxycytidylate deaminase zinc-binding region
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Adat2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tRNA wobble adenosine to inosine editing
Cellular Component
Where in the cell the gene product is active
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- tRNA-specific adenosine-34 deaminase activity