Snrpf Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in cytosol and nucleus. Predicted to be part of several cellular components, including methylosome; nucleus; and pICln-Sm protein complex. Is expressed in central nervous system and sensory organ. Orthologous to human SNRPF (small nuclear ribonucleoprotein polypeptide F). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snrpf |
| Official Name | small nuclear ribonucleoprotein polypeptide F [Source:MGI Symbol;Acc:MGI:1917128] |
| Ensembl ID | ENSMUSG00000020018 |
| Bio databases IDs | |
| Aliases | small nuclear ribonucleoprotein polypeptide F |
| Synonyms | 2010013O18Rik, LOC687845, small nuclear ribonucleoprotein polypeptide F, SMF, snRNP-F |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Snrpf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sm and related proteins
- protein binding
- RNA binding
Pathways
Biological processes and signaling networks where the Snrpf gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colon cancer
- non-small cell lung cancer
- chronic periodontal disease
- infection by Influenza A virus subtype H1N1
role in cell
- production in
- apoptosis
- cell viability
- replication in
- splicing by
- alternative splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- catalytic step 2 spliceosome
- cytosol
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Snrpf gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- nuclear mRNA splicing, via spliceosome
- spliceosomal snRNP assembly
Cellular Component
Where in the cell the gene product is active
- U5 snRNP
- spliceosomal complex
- U2-type spliceosomal complex
- U7 snRNP
- U2 snRNP
- U1 snRNP
- U4 snRNP
- nucleoplasm
- U12-type spliceosomal complex
- nucleus
- pICln-Sm protein complex
- catalytic step 2 spliceosome
- methylosome
- U4/U6 x U5 tri-snRNP complex
- SMN-Sm protein complex
- U2-type catalytic step 2 spliceosome
- cytosol
- U2-type precatalytic spliceosome
- small nuclear ribonucleoprotein complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding