Washc3 Gene Summary [Mouse]
Predicted to be involved in actin filament polymerization and exocytosis. Part of WASH complex. Is expressed in several structures, including adipose tissue; central nervous system; eye; liver; and thymus primordium. Orthologous to human WASHC3 (WASH complex subunit 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Washc3 |
| Official Name | WASH complex subunit 3 [Source:MGI Symbol;Acc:MGI:1914532] |
| Ensembl ID | ENSMUSG00000020056 |
| Bio databases IDs | |
| Aliases | WASH complex subunit 3 |
| Synonyms | 2900091E11RIK, 5730495F03Rik, AD016, CCD53, CCDC53, CGI-116, RGD1563761, WASH complex subunit 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Washc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Subunit CCDC53 of WASH complex
- helical domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Washc3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- actin filament polymerization
- endosomal transport
- exocytosis
- regulation of Arp2/3 complex-mediated actin nucleation
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- WASH complex
Molecular Function
What the gene product does at the molecular level
- protein binding