Mob1b Gene Summary [Mouse]

Predicted to enable kinase binding activity and protein serine/threonine kinase activator activity. Predicted to be involved in hippo signaling and regulation of protein autophosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human MOB1B (MOB kinase activator 1B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Mob1b
Official Name
MOB kinase activator 1B [Source:MGI Symbol;Acc:MGI:1915723]
Ensembl ID
ENSMUSG00000006262
Bio databases IDs NCBI: 68473 Ensembl: ENSMUSG00000006262
Aliases MOB kinase activator 1B
Synonyms 1110003E08Rik, B230364F10, MATS2, MOB4A, MOB kinase activator 1B, MOBKL1A
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mob1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein kinase activator
  • kinase binding
  • kinase activator
  • protein binding
  • Mob1/phocein family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • neoplasia
  • cancer
  • tumorigenesis
  • atrial fibrillation
  • diabetes mellitus
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mob1b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of protein phosphorylation
  • hippo signaling cascade
  • regulation of protein autophosphorylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • extracellular vesicular exosome
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • kinase activator activity
  • protein binding
  • protein serine/threonine kinase activator activity
  • metal ion binding
  • protein kinase activator activity
  • kinase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.