Chac2 Gene Summary [Mouse]
Predicted to enable glutathione specific gamma-glutamylcyclotransferase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human CHAC2 (ChaC glutathione specific gamma-glutamylcyclotransferase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Chac2 |
| Official Name | ChaC, cation transport regulator 2 [Source:MGI Symbol;Acc:MGI:1915294] |
| Ensembl ID | ENSMUSG00000020309 |
| Bio databases IDs | |
| Aliases | ChaC, cation transport regulator 2 |
| Synonyms | ChaC, cation transport regulator 2, ChaC glutathione specific gamma-glutamylcyclotransferase 2, ChaC glutathione specific γ-glutamylcyclotransferase 2, GCG1, RGD1309120 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Chac2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- amidine lyase
- GGCT_like
- gamma-glutamylcyclotransferase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Chac2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glutathione biosynthetic process
- glutathione catabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- gamma-glutamylcyclotransferase activity