Erlec1 Gene Summary [Mouse]
Predicted to enable unfolded protein binding activity. Predicted to be involved in negative regulation of retrograde protein transport, ER to cytosol and retrograde protein transport, ER to cytosol. Predicted to be active in endoplasmic reticulum lumen. Is expressed in mandible; maxilla; orbito-sphenoid; and rib. Orthologous to human ERLEC1 (endoplasmic reticulum lectin 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Erlec1 |
| Official Name | endoplasmic reticulum lectin 1 [Source:MGI Symbol;Acc:MGI:1914003] |
| Ensembl ID | ENSMUSG00000020311 |
| Bio databases IDs | |
| Aliases | endoplasmic reticulum lectin 1 |
| Synonyms | 4933407N01Rik, C2orf30, CIM, CL24936, CL25084, endoplasmic reticulum lectin 1, HEL117, RGD1306508, XTP3-B, XTP3TPB |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Erlec1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Glucosidase II beta subunit-like protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- Endoplasmic Reticulum
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Erlec1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endoplasmic reticulum unfolded protein response
- retrograde protein transport, ER to cytosol
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- endoplasmic reticulum quality control compartment
Molecular Function
What the gene product does at the molecular level
- protein binding
- unfolded protein binding