Mboat2 Gene Summary [Mouse]
Enables 1-acylglycerophosphocholine O-acyltransferase activity and 1-acylglycerophosphoethanolamine O-acyltransferase activity. Involved in phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; and regulation of chondrocyte differentiation. Located in endoplasmic reticulum membrane. Is expressed in several structures, including T1 rib costal cartilage; alimentary system; genitourinary system; nervous system; and respiratory system. Orthologous to human MBOAT2 (membrane bound O-acyltransferase domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mboat2 |
| Official Name | membrane bound O-acyltransferase domain containing 2 [Source:MGI Symbol;Acc:MGI:1914466] |
| Ensembl ID | ENSMUSG00000020646 |
| Bio databases IDs | |
| Aliases | membrane bound O-acyltransferase domain containing 2 |
| Synonyms | 2810049G06Rik, LOC129642, LPAAT, LPCAT, LPCAT4, LPEAT, LPLAT13, LPLAT 2, membrane bound O-acyltransferase domain containing 2, Moact2, OACT2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mboat2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 1-acylglycerol-3-phosphate O-acyltransferase
- 2-acylglycerol-3-phosphate O-acyltransferase
- MBOAT, membrane-bound O-acyltransferase family
- 1-acylglycerophosphocholine O-acyltransferase
- enzyme
- O-acyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mboat2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylcholine acyl-chain remodeling
- phosphatidylethanolamine acyl-chain remodeling
- regulation of chondrocyte differentiation
- phospholipid biosynthetic process
- phosphatidylserine acyl-chain remodeling
- lipid modification
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
Molecular Function
What the gene product does at the molecular level
- 1-acylglycerol-3-phosphate O-acyltransferase activity
- transferase activity, transferring acyl groups
- 1-acylglycerophosphocholine O-acyltransferase activity
- 2-acylglycerol-3-phosphate O-acyltransferase activity