Hhipl1 Gene Summary [Mouse]
Acts upstream of or within several processes, including artery development; cell population proliferation; and smoothened signaling pathway. Is active in extracellular region. Is expressed in adrenal gland; cartilage; nervous system; stomach; and testis. Orthologous to human HHIPL1 (HHIP like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hhipl1 |
| Official Name | hedgehog interacting protein-like 1 [Source:MGI Symbol;Acc:MGI:1919265] |
| Ensembl ID | ENSMUSG00000021260 |
| Bio databases IDs | |
| Aliases | hedgehog interacting protein-like 1 |
| Synonyms | 1600002O04Rik, AK129450, hedgehog interacting protein-like 1, HHIP-like 1, KIAA1822, mKIAA1822, RGD1311698, UNQ9245 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hhipl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Scavenger receptor cysteine-rich domain
- protein binding
- Folate receptor family
- Scavenger receptor Cys-rich
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hhipl1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- extracellular region