Dhrs4 Gene Summary [Mouse]
Enables retinal dehydrogenase activity. Acts upstream of or within retinal metabolic process. Located in mitochondrion and peroxisome. Orthologous to several human genes including DHRS4 (dehydrogenase/reductase 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dhrs4 |
| Official Name | dehydrogenase/reductase (SDR family) member 4 [Source:MGI Symbol;Acc:MGI:90169] |
| Ensembl ID | ENSMUSG00000022210 |
| Bio databases IDs | |
| Aliases | dehydrogenase/reductase (SDR family) member 4 |
| Synonyms | CR, D14Ucla2, dehydrogenase/reductase 4, mouNRDR, NDRD, PHCR, PSCD, RRD |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dhrs4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NADP-retinol dehydrogenase
- Rossmann-fold NAD(P)(+)-binding proteins
- 3-keto sterol reductase
- retinal dehydrogenase
- pteridine reductase
- enzyme
- Enoyl-(Acyl carrier protein) reductase
- 3-oxoacyl-(acyl-carrier-protein) reductase, putative
- identical protein binding
- alcohol dehydrogenase [NAD(P)]
- carbonyl reductase (NADPH)
- sepiapterin reductase
- short chain dehydrogenase
- NADH or NADPH:quinone oxidoreductase
Pathways
Biological processes and signaling networks where the Dhrs4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Mitochondria
- peroxisome membrane
- peroxisomes