HHIPL1 Gene Summary [Human]

This gene encodes a protein that belongs to the glucose/sorbosone dehydrogenase family. The encoded protein also contains a domain that binds folate and reduced folic acid derivatives. [provided by RefSeq, Jul 2016]

Details

Type
Protein Coding
Official Symbol
HHIPL1
Official Name
HHIP like 1 [Source:HGNC Symbol;Acc:HGNC:19710]
Ensembl ID
ENSG00000182218
Bio databases IDs NCBI: 84439 Ensembl: ENSG00000182218
Aliases HHIP like 1
Synonyms 1600002O04Rik, AK129450, hedgehog interacting protein-like 1, HHIP-like 1, KIAA1822, mKIAA1822, RGD1311698, UNQ9245
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HHIPL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Scavenger receptor cysteine-rich domain
  • protein binding
  • Folate receptor family
  • Scavenger receptor Cys-rich

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • abdominal aortic aneurysm
  • coronary artery disease
  • COVID-19
  • myocardial infarction
  • heart disease
  • carpal tunnel syndrome
regulated by
role in cell
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human HHIPL1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane
  • extracellular region

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.