Ankra2 Gene Summary [Mouse]
Enables histone deacetylase binding activity. Predicted to be involved in regulation of gene expression and regulation of protein-containing complex assembly. Located in cytoplasm; membrane; and nucleus. Is expressed in main olfactory bulb. Orthologous to human ANKRA2 (ankyrin repeat family A member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ankra2 |
| Official Name | ankyrin repeat, family A (RFXANK-like), 2 [Source:MGI Symbol;Acc:MGI:1915808] |
| Ensembl ID | ENSMUSG00000021661 |
| Bio databases IDs | |
| Aliases | ankyrin repeat, family A (RFXANK-like), 2 |
| Synonyms | 1110004M18Rik, ANKRA, ankyrin repeat family A member 2, LOC100910438 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ankra2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ubiquitin protein ligase binding
- transcription regulator
- Ankyrin repeats (many copies)
- protein kinase binding
- Ankyrin repeats (3 copies)
- histone deacetylase binding
- low-density lipoprotein receptor binding
- protein binding
- Ankyrin repeat
- ankyrin repeats
Pathways
Biological processes and signaling networks where the Ankra2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- cell periphery
- cellular membrane
- Nucleus
- Plasma Membrane
- cytosol
- nuclear foci
- neurites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ankra2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of gene expression
- regulation of protein complex assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoskeleton
- membrane
- cytosol
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- ubiquitin protein ligase binding
- low-density lipoprotein particle receptor binding
- protein binding
- histone deacetylase binding