Poc5 Gene Summary [Mouse]

Predicted to be involved in centriole elongation; eye photoreceptor cell development; and negative regulation of centriole elongation. Predicted to be located in cytosol; microtubule organizing center; and nucleoplasm. Predicted to be active in photoreceptor connecting cilium. Is expressed in central nervous system; ganglia; and sensory organ. Orthologous to human POC5 (POC5 centriolar protein). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Poc5
Official Name
POC5 centriolar protein [Source:MGI Symbol;Acc:MGI:1914713]
Ensembl ID
ENSMUSG00000021671
Bio databases IDs NCBI: 67463 Ensembl: ENSMUSG00000021671
Aliases POC5 centriolar protein
Synonyms 1200014M14Rik, C5orf37, POC5 centriolar protein, RGD1310597
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Poc5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • insomnia
  • diabetes mellitus
  • obesity
  • syndromic retinitis pigmentosa
  • metabolic syndrome X
  • migraines
  • primary snoring
  • overnutrition
regulated by
role in cell
  • elongation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • centrosome
  • centriole
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Poc5 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • centriole
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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