Capn7 Gene Summary [Mouse]
Predicted to enable MIT domain binding activity and cysteine-type endopeptidase activity. Involved in proteolysis. Predicted to be located in centrosome and cytosol. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Orthologous to human CAPN7 (calpain 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Capn7 |
| Official Name | calpain 7 [Source:MGI Symbol;Acc:MGI:1338030] |
| Ensembl ID | ENSMUSG00000021893 |
| Bio databases IDs | |
| Aliases | calpain 7 |
| Synonyms | AU022319, CALPAIN7, PALBH |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Capn7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Microtubule Interacting and Trafficking molecule domain
- MIT (microtubule interacting and transport) domain
- Calpain family cysteine protease
- endopeptidase
- MIT
- peptidase
- protein domain specific binding
- MIT domain
- protein binding
- Calpain_III
- CysPc
Pathways
Biological processes and signaling networks where the Capn7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- centrosome
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Capn7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- self proteolysis
- proteolysis
- positive regulation of epithelial cell migration
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- cysteine-type endopeptidase activity
- endopeptidase activity
- calcium-dependent cysteine-type endopeptidase activity