Zc3h13 Gene Summary [Mouse]
Predicted to enable zinc ion binding activity. Involved in regulation of stem cell population maintenance. Located in nuclear speck. Part of RNA N6-methyladenosine methyltransferase complex. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZC3H13 (zinc finger CCCH-type containing 13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Zc3h13 |
| Official Name | zinc finger CCCH type containing 13 [Source:MGI Symbol;Acc:MGI:1914552] |
| Ensembl ID | ENSMUSG00000022000 |
| Bio databases IDs | |
| Aliases | zinc finger CCCH type containing 13 |
| Synonyms | 2600010B19RIK, 3110050K21RIK, 4930570G11Rik, KIAA0853, RGD1307729, Xio, zinc finger CCCH-type containing 13 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zc3h13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- zinc finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- liver cancer
- colorectal cancer
- lung adenocarcinoma
- lung adenocarcinoma formation
- organismal death
- hepatocellular carcinoma
- cervical cancer
- melanoma
- melanoma cancer
role in cell
- expression in
- migration
- apoptosis
- proliferation
- activation in
- cisplatin sensitivity
- G2/M phase
- invasion by
- production in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Nucleus
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zc3h13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- regulation of stem cell maintenance
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- metal ion binding