Snrnp40 Gene Summary [Mouse]
Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in cytosol and nuclear speck. Predicted to be part of U2-type catalytic step 2 spliceosome and U4/U6 x U5 tri-snRNP complex. Is expressed in cerebral cortex ventricular layer; liver; lung; metanephros; and submandibular gland primordium. Orthologous to human SNRNP40 (small nuclear ribonucleoprotein U5 subunit 40). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snrnp40 |
| Official Name | small nuclear ribonucleoprotein 40 (U5) [Source:MGI Symbol;Acc:MGI:1913835] |
| Ensembl ID | ENSMUSG00000074088 |
| Bio databases IDs | |
| Aliases | small nuclear ribonucleoprotein 40 (U5) |
| Synonyms | 0610009C03Rik, 40K, HPRP8BP, PRP8BP, PRPF8BP, RGD1309198, small nuclear ribonucleoprotein 40 (U5), small nuclear ribonucleoprotein U5 subunit 40, SPF38, U5-40, U5-40K, U5 snrnp 40 kda, WDR57 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Snrnp40 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- protein binding
Pathways
Biological processes and signaling networks where the Snrnp40 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- catalytic step 2 spliceosome
- cytosol
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Snrnp40 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing, via transesterification reactions
- RNA splicing
- RNA processing
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- catalytic step 2 spliceosome
- nuclear speck
- U4/U6 x U5 tri-snRNP complex
- U5 snRNP
- U2-type catalytic step 2 spliceosome
- cytosol
- small nucleolar ribonucleoprotein complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding