Gpr180 Gene Summary [Mouse]

Acts upstream of or within several processes, including fat cell differentiation; protein phosphorylation; and response to food. Predicted to be located in membrane. Is expressed in embryo. Orthologous to human GPR180 (G protein-coupled receptor 180). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gpr180
Official Name
G protein-coupled receptor 180 [Source:MGI Symbol;Acc:MGI:1930949]
Ensembl ID
ENSMUSG00000022131
Bio databases IDs NCBI: 58245 Ensembl: ENSMUSG00000022131
Aliases G protein-coupled receptor 180
Synonyms E130016I23Rik, G protein-coupled receptor 180, ITR, LOC144874
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr180 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Lung seven transmembrane receptor

Pathways

Biological processes and signaling networks where the Gpr180 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
regulated by
  • interferon alpha
  • SNX27
  • Retromer
disease
  • late-onset Alzheimer disease
phenotypes
  • abnormal artery morphology
  • decreased susceptibility to injury
role in cell
  • differentiation
  • cell viability

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr180 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • response to pheromone

Cellular Component

Where in the cell the gene product is active
  • membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.