Ankhd1 Gene Summary [Mouse]
Predicted to be involved in innate immune response. Predicted to be active in cytoplasm. Is expressed in blastocyst; brain; olfactory epithelium; and spinal cord. Orthologous to several human genes including ANKHD1 (ankyrin repeat and KH domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ankhd1 |
| Official Name | ankyrin repeat and KH domain containing 1 [Source:MGI Symbol;Acc:MGI:1921733] |
| Ensembl ID | ENSMUSG00000024483 |
| Bio databases IDs | |
| Aliases | ankyrin repeat and KH domain containing 1 |
| Synonyms | 1110004O12Rik, 4933432B13RIK, 9130019P20RIK, A530027J04RIK, A630021B20Rik, ankyrin repeat and KH domain containing 1, APAP2, FLJ20288, MASK, MASK1, mFLJ00246, mKIAA1085, PP2500, VBARP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ankhd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- MAP7 (E-MAP-115) family
- KH domain
- K homology (KH) RNA-binding domain, type I
- Ankyrin repeats (3 copies)
- K homology RNA-binding domain
- protein binding
- Ankyrin repeat
- ankyrin repeats
Pathways
Biological processes and signaling networks where the Ankhd1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- renal cell carcinoma
- cancer
- bipolar I disorder
- bipolar disorder
- brain cancer
- central nervous system cancer
- head and neck cancer
- head and neck neoplasia
- renal cell cancer
role in cell
- proliferation
- phosphorylation in
- expression in
- G2/M phase
- degradation in
- number
- formation in
- formation
- breakage in
- radiosensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ankhd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding