Rida Gene Summary [Mouse]
Predicted to enable several functions, including 2-iminobutanoate deaminase activity; identical protein binding activity; and long-chain fatty acid binding activity. Predicted to be involved in negative regulation of epithelial cell proliferation and negative regulation of gene expression. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human RIDA (reactive intermediate imine deaminase A homolog). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rida |
| Official Name | reactive intermediate imine deaminase A homolog [Source:MGI Symbol;Acc:MGI:1095401] |
| Ensembl ID | ENSMUSG00000022323 |
| Bio databases IDs | |
| Aliases | reactive intermediate imine deaminase A homolog |
| Synonyms | 1QAH B, Chain B, perchloric acid-soluble protein-a translational inhibitor, hp14.5, HR12, HRP12, HRSP12, l-Psp, L-PSP, chain b, P14.5, PSP, PSP1, reactive intermediate imine deaminase A homolog, Ribonuclease uk114, Ribonuclease UK114, chain B, rp14.5, UK114 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rida often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- Non-5' phosphomonoester producing endoribonuclease
- mRNA binding
- fatty acid binding
- deaminase
- enzyme
- protein binding
- identical protein binding
- transition metal ion binding
- YjgF_YER057c_UK114_family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insulin-dependent diabetes mellitus
- insulitis
role in cell
- expression in
- proliferation
- translation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Mitochondria
- cytosol
- mitochondrial matrix
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rida gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA destabilization
- L-threonine catabolic process to glycine
- lipid metabolic process
- mRNA catabolic process
- negative regulation of translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- peroxisome
- extracellular vesicular exosome
- cytoplasm
- mitochondrial matrix
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- mRNA binding
- endoribonuclease activity, producing 3'-phosphomonoesters
- deaminase activity