Tbc1d31 Gene Summary [Mouse]

Predicted to enable molecular adaptor activity. Predicted to be involved in cilium assembly. Predicted to be located in centriolar satellite. Predicted to be active in ciliary basal body. Orthologous to human TBC1D31 (TBC1 domain family member 31). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tbc1d31
Official Name
TBC1 domain family, member 31 [Source:MGI Symbol;Acc:MGI:2684931]
Ensembl ID
ENSMUSG00000022364
Bio databases IDs NCBI: 210544 Ensembl: ENSMUSG00000022364
Aliases TBC1 domain family, member 31
Synonyms 4B3, D330013L20Rik, Gm85, LOC683915, MGC21654, TBC1 domain family member 31, TBC1 domain family, member 31, WDR67
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tbc1d31 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • YscO-like protein
  • Rab-GTPase-TBC domain
  • Domain of unknown function (DUF4515)
  • RNase Y N-terminal region
  • Arginine and glutamate-rich 1
  • Ezrin/radixin/moesin, alpha-helical domain
  • Domain in Tre-2, BUB2p, and Cdc16p
  • pinin/SDK/memA/ protein conserved region
  • WD domain, G-beta repeat
  • WD40
  • protein binding
  • Tropomyosin
  • Family of unknown function (DUF5384)
  • WD40 repeats
  • MAP7 (E-MAP-115) family
  • Chromatin assembly factor 1 complex p150 subunit, N-terminal
  • Trichohyalin-plectin-homology domain
  • ClassIIa_HDAC_Gln-rich-N
  • Domain of unknown function (DUF4200)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • idiopathic scoliosis
regulated by
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • basal bodies
  • centrosome
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tbc1d31 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium morphogenesis

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cilium basal body
  • cytoplasm
  • centriolar satellite

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • binding, bridging

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.