Gtsf1 Gene Summary [Mouse]
Predicted to enable tRNA binding activity. Involved in piRNA-mediated gene silencing by mRNA destabilization and secondary piRNA processing. Located in cytoplasm. Is active in piP-body. Is expressed in gonad. Orthologous to human GTSF1 (gametocyte specific factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gtsf1 |
| Official Name | gametocyte specific factor 1 [Source:MGI Symbol;Acc:MGI:1921424] |
| Ensembl ID | ENSMUSG00000022487 |
| Bio databases IDs | |
| Aliases | gametocyte specific factor 1 |
| Synonyms | 1700006H03Rik, Cue110, FAM112B, gametocyte specific factor 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gtsf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA binding
- U11-48K-like CHHC zinc finger
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic ribonucleoprotein granule
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gtsf1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- tRNA binding