Ccdc14 Gene Summary [Mouse]

Predicted to be involved in protein localization to centrosome. Predicted to be located in centrosome. Predicted to be active in centriolar satellite. Orthologous to human CCDC14 (coiled-coil domain containing 14). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Retained Intron
Official Symbol
Ccdc14
Official Name
coiled-coil domain containing 14 [Source:MGI Symbol;Acc:MGI:2443448]
Ensembl ID
ENSMUSG00000022833
Bio databases IDs NCBI: 239839 Ensembl: ENSMUSG00000022833
Aliases coiled-coil domain containing 14
Synonyms coiled-coil domain containing 14, G630039H03Rik, RGD1562189
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccdc14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4201)
  • Coiled-coil domain-containing protein 14
  • Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • drug-induced liver disease
  • small cell lung cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microtubule cytoskeleton
  • cilia
  • basal bodies
  • centrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccdc14 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein localization to centrosome
  • substantia nigra development

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cytoplasm
  • centriolar satellite

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.