Wrap73 Gene Summary [Mouse]
Predicted to be involved in mitotic spindle assembly and positive regulation of non-motile cilium assembly. Predicted to be located in centrosome and ciliary basal body. Predicted to be part of MWP complex. Predicted to be active in microtubule organizing center. Is expressed in cerebral cortex and cerebral cortex mantle layer. Orthologous to human WRAP73 (WD repeat containing, antisense to TP73). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wrap73 |
| Official Name | WD repeat containing, antisense to Trp73 [Source:MGI Symbol;Acc:MGI:1891749] |
| Ensembl ID | ENSMUSG00000029029 |
| Bio databases IDs | |
| Aliases | WD repeat containing, antisense to Trp73 |
| Synonyms | 2610044M17Rik, 5330425N03Rik, Dd57, WDR8, WD repeat containing, antisense to TP73, WD repeat containing, antisense to Trp73 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wrap73 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- basal bodies
- centrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wrap73 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell projection organization
- spindle assembly involved in mitosis
Cellular Component
Where in the cell the gene product is active
- centrosome
- microtubule organizing center
- cilium basal body
- centriole
- cytoplasm
- centriolar satellite
Molecular Function
What the gene product does at the molecular level
- protein binding