Cfap298 Gene Summary [Mouse]
Predicted to be involved in cilium assembly and regulation of cilium movement. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 26. Orthologous to human CFAP298 (cilia and flagella associated protein 298). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cfap298 |
| Official Name | cilia and flagella associate protien 298 [Source:MGI Symbol;Acc:MGI:1915251] |
| Ensembl ID | ENSMUSG00000022972 |
| Bio databases IDs | |
| Aliases | cilia and flagella associate protien 298 |
| Synonyms | 1110004E09Rik, C21orf48, C21orf59, CILD26, cilia and flagella associated protein 298, cilia and flagella associate protien 298, DNAAF16, FBB18, Kur, RGD1306954 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cfap298 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cilia- and flagella-associated protein 298
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- basal bodies
- centrosome
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cfap298 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- regulation of cilium movement
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoskeleton
- cilium
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding