Plxnb1

Enables GTPase activating protein binding activity and semaphorin receptor activity. Involved in several processes, including negative regulation of osteoblast proliferation; nervous system development; and positive regulation of intracellular signal transduction. Acts upstream of or within positive regulation of axonogenesis. Part of semaphorin receptor complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PLXNB1 (plexin B1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Plxnb1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Plxnb1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Plxnb1 gene, providing context for its role in the cell.