Cep89 Gene Summary [Mouse]
Predicted to be involved in cilium assembly and mitochondrion organization. Located in centriole and motile cilium. Part of ciliary transition fiber. Is expressed in cerebral cortex. Orthologous to human CEP89 (centrosomal protein 89). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Cep89 |
| Official Name | centrosomal protein 89 [Source:MGI Symbol;Acc:MGI:1919390] |
| Ensembl ID | ENSMUSG00000023072 |
| Bio databases IDs | |
| Aliases | centrosomal protein 89 |
| Synonyms | 2610507L03Rik, CCDC123, centrosomal protein 89, CEP123, RGD1311730 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep89 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- ciliary transition fiber
- non-motile cilium
- cilia
- basal bodies
- centrosome
- centriole
- cytosol
- mitochondrial intermembrane space
- nuclear bodies
- spindle pole
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep89 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- synaptic transmission
- mitochondrion organization
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- motile cilium
- centrosome
- centriole
- spindle pole
- cytosol
- synapse
Molecular Function
What the gene product does at the molecular level
- protein binding