Cep83 Gene Summary [Mouse]

Predicted to enable identical protein binding activity. Acts upstream of or within cilium assembly and establishment of centrosome localization. Located in centriole. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in nephronophthisis 18. Orthologous to human CEP83 (centrosomal protein 83). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cep83
Official Name
centrosomal protein 83 [Source:MGI Symbol;Acc:MGI:1924298]
Ensembl ID
ENSMUSG00000020024
Bio databases IDs NCBI: 77048 Ensembl: ENSMUSG00000020024
Aliases centrosomal protein 83
Synonyms 2600001G24Rik, 4921537D05Rik, 5730513H21Rik, CCDC41, centrosomal protein 83, NPHP18, NY-REN-58, RGD1359593
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep83 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • nephronophthisis type 18
  • ciliopathy
role in cell
  • assembly
  • secretion by
  • docking

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • ciliary transition fiber
  • centrosome
  • Golgi Apparatus
  • centriole
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep83 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium morphogenesis
  • establishment of centrosome localization
  • vesicle docking
  • protein localization to centrosome

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • centriole
  • cytosol
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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