Rpl28 Gene Summary [Mouse]

A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; translation at postsynapse; and translation at presynapse. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in several structures, including extraembryonic component; gonad; intestine; liver; and lung. Orthologous to human RPL28 (ribosomal protein L28). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rpl28
Official Name
ribosomal protein L28 [Source:MGI Symbol;Acc:MGI:101839]
Ensembl ID
ENSMUSG00000030432
Bio databases IDs NCBI: 19943 Ensembl: ENSMUSG00000030432
Aliases ribosomal protein L28
Synonyms D7Wsu21e, eL28, L28, LOC107987271, Ribosomal protein L28
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl28 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • Ribosomal L28e protein family
  • protein binding
  • RNA binding

Pathways

Biological processes and signaling networks where the Rpl28 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • myelodysplastic syndrome
  • diabetes mellitus
  • breast cancer
  • survival
  • androgenic alopecia
  • ischemic stroke
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • amphisome
  • cytoplasmic ribonucleoprotein granule
  • ribosome
  • cytosol
  • synapse
  • perikaryon
  • dendrites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl28 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cytoplasmic translation
  • translation

Cellular Component

Where in the cell the gene product is active
  • dendrite
  • extracellular vesicular exosome
  • cytosolic ribosome
  • cytoplasm
  • cell body
  • membrane
  • cytosol
  • cytosolic large ribosomal subunit
  • synapse

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.