Cript

Predicted to enable PDZ domain binding activity; microtubule binding activity; and scaffold protein binding activity. Predicted to be involved in several processes, including cytoplasmic microtubule organization; protein localization to microtubule; and regulation of postsynaptic density organization. Predicted to be located in dendrite; neuronal cell body; and postsynaptic density. Predicted to be part of spliceosomal complex. Predicted to be active in dendrite; glutamatergic synapse; and postsynaptic density, intracellular component. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and retina layer. Human ortholog(s) of this gene implicated in Rothmund-Thomson syndrome. Orthologous to human CRIPT (CXXC repeat containing interactor of PDZ3 domain). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cript often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cript gene, providing context for its role in the cell.