Sec11c Gene Summary [Mouse]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase complex. Is expressed in several structures, including alimentary system; cranium; respiratory system; sensory organ; and telencephalon. Orthologous to human SEC11C (SEC11 homolog C, signal peptidase complex subunit). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sec11c
Official Name
SEC11 homolog C, signal peptidase complex subunit [Source:MGI Symbol;Acc:MGI:1913536]
Ensembl ID
ENSMUSG00000024516
Bio databases IDs NCBI: 66286 Ensembl: ENSMUSG00000024516
Aliases SEC11 homolog C, signal peptidase complex subunit
Synonyms 1810029G24Rik, MICROSOMAL SIGNAL PEPTIDASE subunit, SEC11 homolog C, signal peptidase complex subunit, SEC11L3, SPC21, SPCS4C
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sec11c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • serine endopeptidase
  • peptidase
  • protein binding
  • Peptidase_S24_S26

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • insomnia
regulated by
regulates
role in cell
  • molecular cleavage in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endoplasmic reticulum membrane
  • microsomal membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sec11c gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal peptide processing

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • signal peptidase complex

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • serine-type endopeptidase activity
  • peptidase activity

Gene-Specific Assays for Results You Can Trust

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