Pramel7 Gene Summary [Mouse]
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Involved in blastocyst formation and stem cell population maintenance. Acts upstream of or within regulation of ERK1 and ERK2 cascade and somatic stem cell population maintenance. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in 2-cell stage embryo; 4-cell stage embryo; compacted morula; and inner cell mass. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pramel7 |
| Official Name | PRAME like 7 [Source:MGI Symbol;Acc:MGI:2156391] |
| Ensembl ID | ENSMUSG00000025839 |
| Bio databases IDs | |
| Aliases | PRAME like 7 |
| Synonyms | C81180, PRAME like 7, preferentially expressed antigen in melanoma-like 7, RGD1565990 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pramel7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown