Dppa4 Gene Summary [Mouse]
Predicted to enable chromatin binding activity. Acts upstream of or within lung-associated mesenchyme development. Located in nucleus. Is expressed in several structures, including blastocyst; early embryo; foregut; gonad; and nose. Orthologous to human DPPA4 (developmental pluripotency associated 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Dppa4 |
| Official Name | developmental pluripotency associated 4 [Source:MGI Symbol;Acc:MGI:2157525] |
| Ensembl ID | ENSMUSG00000058550 |
| Bio databases IDs | |
| Aliases | developmental pluripotency associated 4 |
| Synonyms | 2410091M23Rik, developmental pluripotency associated 4, ECAT15-1, FLJ10713 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dppa4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dppa2/4 conserved region in higher vertebrates
- protein binding
- Dppa2/4 conserved region
Pathways
Biological processes and signaling networks where the Dppa4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- proliferation
- expression in
- cell death
- differentiation
- development
- self-renewal
- pluripotency
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- detergent-insoluble fractions
- Cytoplasm
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dppa4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lung-associated mesenchyme development
- system development
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- chromatin binding