Gpr39 Gene Summary [Mouse]
Enables G protein-coupled receptor activity. Acts upstream of or within several processes, including adult feeding behavior; cellular response to zinc ion; and regulation of secretion. Predicted to be located in plasma membrane. Orthologous to human GPR39 (G protein-coupled receptor 39). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpr39 |
| Official Name | G protein-coupled receptor 39 [Source:MGI Symbol;Acc:MGI:1918361] |
| Ensembl ID | ENSMUSG00000026343 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 39 |
| Synonyms | 4933415E13Rik, G protein-coupled receptor 39, ZnR |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr39 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Gpr39 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- acute myeloid leukemia
- tumorigenesis
- neuroinflammation
- human papilloma virus infection
- fracture of bone
role in cell
- production in
- expression in
- phosphorylation in
- transmembrane potential
- cell death
- migration
- activation in
- proliferation
- abnormal morphology
- polymerization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr39 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding
- metal ion binding