Enkur Gene Summary [Mouse]
Enables calmodulin binding activity. Involved in flagellated sperm motility. Acts upstream of or within establishment of left/right asymmetry. Located in 9+0 motile cilium; acrosomal vesicle; and sperm principal piece. Is active in axonemal B tubule inner sheath. Is expressed in lung; node; testis; and trachea. Orthologous to human ENKUR (enkurin, TRPC channel interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Enkur |
| Official Name | enkurin, TRPC channel interacting protein [Source:MGI Symbol;Acc:MGI:1918483] |
| Ensembl ID | ENSMUSG00000026679 |
| Bio databases IDs | |
| Aliases | enkurin, TRPC channel interacting protein |
| Synonyms | 4933434I06Rik, C10orf63, CFAP106, enkurin, TRPC channel interacting protein, RGD1309839 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Enkur often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calmodulin-binding
- calmodulin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- flagella
- axonemes
- sperm tail
- acrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Enkur gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm motility
Cellular Component
Where in the cell the gene product is active
- axonemal microtubule
- acrosomal vesicle
- sperm principal piece
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- protein binding
- SH3 domain binding