ENKUR Gene Summary [Human]
This gene encodes a protein that interacts with calmodulin and several transient receptor potential canonical cation channel proteins. The encoded protein may function as an adaptor to localize signal transduction machinery to calcium channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Details
| Type | Protein Coding |
| Official Symbol | ENKUR |
| Official Name | enkurin, TRPC channel interacting protein [Source:HGNC Symbol;Acc:HGNC:28388] |
| Ensembl ID | ENSG00000151023 |
| Bio databases IDs | |
| Aliases | enkurin, TRPC channel interacting protein |
| Synonyms | 4933434I06Rik, C10orf63, CFAP106, enkurin, TRPC channel interacting protein, RGD1309839 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ENKUR often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calmodulin-binding
- calmodulin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- flagella
- axonemes
- sperm tail
- acrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ENKUR gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm motility
Cellular Component
Where in the cell the gene product is active
- axonemal microtubule
- acrosomal vesicle
- sperm principal piece
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- protein binding
- SH3 domain binding