Ttc17 Gene Summary [Mouse]
Predicted to be involved in actin filament polymerization and cilium organization. Predicted to be located in cytosol and plasma membrane. Predicted to be active in actin cytoskeleton and cytoplasm. Orthologous to human TTC17 (tetratricopeptide repeat domain 17). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ttc17 |
| Official Name | tetratricopeptide repeat domain 17 [Source:MGI Symbol;Acc:MGI:1921819] |
| Ensembl ID | ENSMUSG00000027194 |
| Bio databases IDs | |
| Aliases | tetratricopeptide repeat domain 17 |
| Synonyms | 9130020K17RIK, D2Bwg1005e, LOC103695175, tetratricopeptide repeat domain 17 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ttc17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ClassIIa_HDAC_Gln-rich-N
- Tetratricopeptide repeats
- protein binding
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- coronary artery disease
- venous thromboembolism
- ischemic stroke
- idiopathic scoliosis
regulated by
- dithiothreitol
- brefeldin A
- thapsigargin
- Z-LLL-CHO
- tunicamycin
- Human herpesvirus 1 strain KOS
- levodopa
role in cell
- organization
- polymerization
- co-localization in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- actin cytoskeleton
- Plasma Membrane
- Endoplasmic Reticulum
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ttc17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- actin filament polymerization
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- actin cytoskeleton
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding