Snap23 Gene Summary [Mouse]
Predicted to enable SNAP receptor activity and syntaxin binding activity. Acts upstream of or within exocytosis. Located in cytoplasmic vesicle and plasma membrane. Part of SNARE complex. Is expressed in cerebral cortex ventricular layer; cortical plate; and testis. Orthologous to human SNAP23 (synaptosome associated protein 23). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snap23 |
| Official Name | synaptosomal-associated protein 23 [Source:MGI Symbol;Acc:MGI:109356] |
| Ensembl ID | ENSMUSG00000027287 |
| Bio databases IDs | |
| Aliases | synaptosomal-associated protein 23 |
| Synonyms | HsT17016, SNAP23A, SNAP23B, Sndt, synaptosomal-associated protein 23, synaptosome associated protein 23, Syndet |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Snap23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SNAP receptor
- SNAP-25 family
- cytoplasmic domain
- Helical region found in SNAREs
- coiled-coil domain
- protein binding
- SNARE motif
- zDHHC ankyrin repeat binding domain
- cysteine rich domain
- transporter
- phosphorylation site
- syntaxin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- thrombocytopenia
- passive systemic anaphylaxis
role in cell
- number
- exocytosis by
- expression in
- production in
- phagocytosis by
- migration
- invasion by
- replication in
- survival
- morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- plasma membrane fraction
- raft fractions
- membrane fraction
- detergent resistant lipid raft fraction
- glutaminergic synapse
- Cytoplasm
- invadopodia
- cilia
- cell surface
- postsynaptic region
- cellular membrane
- endosomes
- vesicles
- Mitochondria
- actin filaments
- lipid droplets
- granules
- tertiary granule membrane
- specific granule membrane
- cytosol
- basal membrane
- nucleoplasm
- alpha granule membranes
- synapse
- vacuolar apical compartments
- cytoplasmic vesicles
- azurophil granules
- specific granules
- tertiary granules
- membrane rafts
- membrane processes
- phagosomes
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Snap23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane fusion
- synaptic vesicle priming
- vesicle targeting
- protein transport
- synaptic vesicle fusion to presynaptic membrane
- post-Golgi vesicle-mediated transport
- exocytosis
- histamine secretion by mast cell
Cellular Component
Where in the cell the gene product is active
- neuron projection
- plasma membrane
- nucleoplasm
- adherens junction
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- specific granule
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
- azurophil granule
- mitochondrion
- phagocytic vesicle membrane
- SNARE complex
- tertiary granule membrane
- specific granule membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- syntaxin-1 binding
- SNAP receptor activity