Scamp2 Gene Summary [Mouse]

Predicted to be involved in protein transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in recycling endosome membrane and trans-Golgi network membrane. Orthologous to human SCAMP2 (secretory carrier membrane protein 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Scamp2
Official Name
secretory carrier membrane protein 2 [Source:MGI Symbol;Acc:MGI:1346518]
Ensembl ID
ENSMUSG00000040188
Bio databases IDs NCBI: 24044 Ensembl: ENSMUSG00000040188
Aliases secretory carrier membrane protein 2
Synonyms Sc2, secretory carrier membrane protein 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Scamp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SCAMP family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • multiple sclerosis
  • breast carcinoma
  • estrogen receptor positive breast cancer
regulated by
  • EZH2
  • insulin
  • trichostatin A
regulates
role in cell
  • growth
  • transport
  • exocytosis by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • perinuclear Golgi regions
  • cell periphery
  • membrane surface
  • cellular membrane
  • Plasma Membrane
  • vesicles
  • Golgi Apparatus
  • granules
  • trans Golgi network
  • endosomal membrane
  • recycling endosomes
  • axons
  • axon terminals

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Scamp2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein transport
  • post-Golgi vesicle-mediated transport

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • intracellular membrane-bounded organelle
  • membrane
  • Golgi apparatus
  • recycling endosome membrane
  • trans-Golgi network membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.