Ctnnbl1 Gene Summary [Mouse]
Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of apoptotic process and somatic diversification of immunoglobulins. Predicted to act upstream of or within apoptotic process. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of Prp19 complex and spliceosomal complex. Is expressed in cerebral cortex ventricular layer; embryo; limb; and limb mesenchyme. Human ortholog(s) of this gene implicated in colorectal cancer; immunodeficiency 99; and morbid obesity. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ctnnbl1 |
| Official Name | catenin, beta like 1 [Source:MGI Symbol;Acc:MGI:1913892] |
| Ensembl ID | ENSMUSG00000027649 |
| Bio databases IDs | |
| Aliases | catenin, beta like 1 |
| Synonyms | 5730471K09Rik, C20orf33, catenin beta like 1, catenin, beta like 1, catenin β like 1, catenin, β like 1, dJ633O20.1, IMD99, NAP, NYD-SP19, P14L, PP8304 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ctnnbl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Catenin-beta-like, Arm-motif containing nuclear
- enzyme binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- centrosome
- cytosol
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ctnnbl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of apoptotic process
- adaptive immune response
- somatic diversification of immunoglobulins
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- membrane
- spliceosomal complex
- cytosol
- Prp19 complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- enzyme binding