Tm4sf4 Gene Summary [Mouse]
Predicted to be active in membrane. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and hemolymphoid system gland. Orthologous to human TM4SF4 (transmembrane 4 L six family member 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tm4sf4 |
| Official Name | transmembrane 4 superfamily member 4 [Source:MGI Symbol;Acc:MGI:2385173] |
| Ensembl ID | ENSMUSG00000027801 |
| Bio databases IDs | |
| Aliases | transmembrane 4 superfamily member 4 |
| Synonyms | ILTMP, LOC108350014, Lrtm4, transmembrane 4 L six family member 4, transmembrane 4 superfamily member 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tm4sf4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- L6 membrane protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- cholecystitis
- colon cancer
- cholelithiasis
- single major depressive episode
- major depression
- coronary artery disease
- gout
- gallstone
- gallbladder polyp
regulates
- actin
role in cell
- proliferation
- migration
- colony formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tm4sf4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tissue regeneration
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding