Saxo1 Gene Summary [Mouse]
Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including cold acclimation; positive regulation of cilium assembly; and protein stabilization. Predicted to be located in motile cilium. Predicted to be active in microtubule cytoskeleton and sperm flagellum. Orthologous to human SAXO1 (stabilizer of axonemal microtubules 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Saxo1 |
| Official Name | stabilizer of axonemal microtubules 1 [Source:MGI Symbol;Acc:MGI:1923061] |
| Ensembl ID | ENSMUSG00000028492 |
| Bio databases IDs | |
| Aliases | stabilizer of axonemal microtubules 1 |
| Synonyms | 4930500O09Rik, C9orf138, FAM154A, LOC100365211, LOC684579, stabilizer of axonemal microtubules 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Saxo1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- basal bodies
- centriole
- axonemes
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Saxo1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell projection organization
- cold acclimation
- protein stabilization
- positive regulation of flagellum assembly
- cellular response to cold
Cellular Component
Where in the cell the gene product is active
- centrosome
- motile cilium
- axonemal microtubule
- cytoskeleton
- centriole
- cilium basal body
- sperm flagellum
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding