Osgin1 Gene Summary [Mouse]
Predicted to enable growth factor activity. Predicted to be involved in several processes, including negative regulation of cell growth; regulation of apoptotic process; and regulation of cell migration. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human OSGIN1 (oxidative stress induced growth inhibitor 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Osgin1 |
| Official Name | oxidative stress induced growth inhibitor 1 [Source:MGI Symbol;Acc:MGI:1919089] |
| Ensembl ID | ENSMUSG00000074063 |
| Bio databases IDs | |
| Aliases | oxidative stress induced growth inhibitor 1 |
| Synonyms | 1700012B18Rik, BDGI, OKL38, oxidative stress induced growth inhibitor 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Osgin1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- growth factor
Pathways
Biological processes and signaling networks where the Osgin1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- tumorigenesis
- cervical cancer
regulates
- cytochrome C
- reactive oxygen species
- CYCS
role in cell
- growth
- formation
- apoptosis
- cell death
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Osgin1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of cell growth
- signal transduction
- cell differentiation
- regulation of apoptotic process
- regulation of cell migration
- regulation of cell proliferation
Molecular Function
What the gene product does at the molecular level
- growth factor activity
- protein binding