Tm2d1 Gene Summary [Mouse]
Enables G protein-coupled receptor activity and amyloid-beta binding activity. Acts upstream of or within apoptotic signaling pathway. Located in plasma membrane. Orthologous to human TM2D1 (TM2 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tm2d1 |
| Official Name | TM2 domain containing 1 [Source:MGI Symbol;Acc:MGI:2137022] |
| Ensembl ID | ENSMUSG00000028563 |
| Bio databases IDs | |
| Aliases | TM2 domain containing 1 |
| Synonyms | 2310026L18Rik, BBP, BBP-1, LOC682077, LOC685326, TM2 domain containing 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tm2d1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- TM2 domain
- transmembrane domain
- protein binding
- beta-amyloid binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tm2d1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- apoptotic signaling pathway
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding
- beta-amyloid binding